rapid Production of therapeutic Proteins using Plant System
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چکیده
Plant molecular farming is simply defined as the production of proteins therapeutics (PT) in plants, which involves transient gene expression in plants and purification of expressed protein to a great scale for diagnosis, treatment and other applications. This is the rapid, economical, safe and reproducible approach for the production of PT as compared to bacterial and mammalian systems. Protein yield and post-translational modifications are the major roadblocks that can be overcome by high expression strategies includes over expression constructs, suitable plant host systems and glycoengineering of proteins. The inherent ability of ideally producing safe, functional protein is the most striking phenomenon recognised by the pharmaceutical industries and developed many therapeutic products within few weeks to meet escalating demands during pandemic/epidemic outbreaks recently.
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تاریخ انتشار 2017